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The Collagen Connection 胶原蛋白连接

The Collagen Connection  胶原蛋白连接

This unheralded protein plays a key role in keeping us together—literally

The most abundant protein in the human body, collagen is also the main component of connective tissue such as tendons, ligaments, cartilage, bone, and blood vessels.

As we age, the collagen-rich support structure of the skin (known as the dermis) changes. The activity of fibroblasts—cells responsible for making collagen—slows down, which leads to changes that make skin look old.

The collagen production in our joints also slows with age, which may lead to osteoarthritis. And decreased collagen in bone is a key factor in osteoporosis. The amount of collagen determines the number of “bone mineral binding sites.” If the collagen content is low, bone becomes more brittle and fracture risk increases dramatically.

Increasing Collagen

To fight the problem of declining collagen levels, we need to increase the activity of collagen-producing cells. One of the best ways to do this is the use of a special from of silica—choline stabilized orthosilicic acid (ChOSA). In one study, women with signs of aging skin who received 10 mg of ChOSA daily saw a 30 percent improvement in fine lines, 55 percent increased skin elasticity, and a reduction in brittle nails and hair.

ChOSA has also shown benefits in promoting bone health. In a detailed double-blind study of postmenopausal women with low bone density, ChOSA was able to increase the collagen content of the bone by 22 percent and increase bone density by 2 percent. The typical dosage is 6–10 mg per day.

Flavonoids are Critical

Flavonoids are plant pigments that support healthy collagen levels. Especially beneficial are the blue or purple pigments—anthocyanidins and PCOs (short for proanthocyanidin oligomers)—found in grapes, blueberries, and pine bark and grape seed extracts. Among their benefits:

  • They have the ability to crosslink collagen fibers, reinforcing the natural crosslinking that forms the collagen matrix of connective tissue.
  • They inhibit destruction of collagen structures by enzymes secreted by white blood cells during inflammation.

To take advantage of these flavonoids, increase your intake of richly colored berries and other fruits. And supplement with a PCO-rich extract such as grape seed or pine bark (50– 150 mg per day) for general support.

 

这种未被发现的蛋白质在将我们聚集在一起起着至关重要的作用
胶原蛋白是人体中含量最丰富的蛋白质,也是结缔组织的主要成分,如肌腱,韧带,软骨,骨骼和血管。

随着年龄的增长,富含胶原蛋白的皮肤支持结构(称为真皮)会发生变化。成纤维细胞 - 负责制造胶原蛋白的细胞的活性减慢,导致皮肤看起来变老的变化。

我们关节中的胶原蛋白生成也随着年龄的增长而减慢,这可能导致骨关节炎。骨质中胶原蛋白减少是骨质疏松症的关键因素。胶原蛋白的量决定了“骨矿物质结合位点”的数量。如果胶原蛋白含量低,骨骼变得更脆,骨折风险显着增加。

增加胶原蛋白
为了解决胶原蛋白水平下降的问题,我们需要增加胶原蛋白生成细胞的活性。最好的方法之一是使用二氧化硅 - 胆碱稳定的原硅酸(ChOSA)。在一项研究中,每天接受10毫克ChOSA的皮肤衰老迹象的女性细纹改善30%,皮肤弹性增加55%,指甲和头发脆弱减少。

ChOSA也有助于促进骨骼健康。在对骨密度低的绝经后妇女进行的详细双盲研究中,ChOSA能够将骨骼中的胶原蛋白含量增加22%,骨密度增加2%。典型剂量为每天6-10mg。

黄酮类化合物很重要
黄酮类化合物是支持健康胶原蛋白水平的植物色素。特别有益的是蓝色或紫色颜料 - 花青素和PCO(原花青素低聚物的缩写) - 在葡萄,蓝莓,松树皮和葡萄籽提取物中发现。他们的好处包括:

它们具有交联胶原纤维的能力,增强形成结缔组织胶原基质的天然交联。
它们抑制炎症期间白细胞分泌的酶对胶原结构的破坏。
要利用这些黄酮类化合物,可以增加颜色丰富的浆果和其他水果的摄入量。并补充富含PCO的提取物,如葡萄籽或松树皮(每天50-150毫克),以获得一般支持。



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